Inherited Essential Tremor

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Inherited Essential Tremor

Essential Tremor
Other names for Essential Tremor

Familial tremor
Benign essential tremor

Hereditary essential tremor

ET is a progressive nervous system (neurological) disorder that causes involuntary and rhythmic shaking of the hands, head, voice, legs, or trunk.

The inherited variety of essential tremor is an autosomal dominant disorder. An altered gene from just one parent is needed to pass on the condition. If you have a parent with an altered gene for essential tremor, you have a 50% chance of developing the disorder yourself.

Genetics--About 50 percent of the cases of essential tremor are thought to be caused by a genetic risk factor (referred to as familial tremor). Children of a parent who has familial tremor have greater risk of inheriting the condition. Familial forms of essential tremor often appear early in life.

Essential Tremor is caused by overactive cells in the area of the brain called the thalamus. The thalamus is about the size of a walnut and within the brain there are two of them. If there are overactive cells in the right thalamus, the person will have signs of tremor on the left side and vice versa. Some patients suffer from tremor on both sides.

Despite its prevalence, it wasn't until 2013 that essential tremor was given its own specific diagnostic code, one that's distinct from other tremors, in the 10th edition of the World Health Organization's International Statistical Classification of Disease and Related Health Problems (ICD) code book. ICD-10-CM Code for Essential tremor G25.0

ICD-10 code G25.0 for Essential tremor is a medical classification as listed by WHO under the range - Diseases of the nervous system.
In medicine, the word "essential" means there's no known underlying cause for a symptom, which is the case for essential tremor.

The Point of onset can be similarly challenging, as tremor starts as on the is subtle.
As is the case with other degenerative conditions such as Parkinson’s disease, SCA, or dementia, the onset of ET is similarly insidious, as has been well-documented. Indeed, age of onset can be difficult to determine because patients can have difficulty appreciating their tremor early on.

Retrospectively recalling the point of onset can be similarly challenging, as tremor starts as one that is subtle, of low-amplitude, and difficult to distinguish from medication-induced tremor, anxiety-related tremor or other para-normal and/or situational forms of tremor. As with other forms of neurodegeneration, the worsening of tremor in ET then follows a gradual yet progressive clinical course, albeit the pattern of progression differs across patients; there have never been any documented cases of reversion of tremor or cessation of disease once set in motion.

There is a marked and continued rise in disease occurrence (both incidence and prevalence), which is exponential in advanced ages, and which is yet another feature of the neurodegenerative conditions. Furthermore, ET itself has been associated with other neurodegenerative disorders. For example, there is a longstanding association between ET and PD; indeed, having ET increases the risk of developing incident PD four to five-fold. ET & the Cerebellum

Essential tremors (ET) is when you have uncontrolled shaking movements in parts of your body - most commonly the arms and hands. It tends to occur in families. It is mild in some people but can become severe, debilitating, and demoralizing. First and foremost, Essential Tremor can begin at any age from ages 1 to 100. ET doesn’t discriminate with age, race, sex, or national origin.